Bioengineering of the Skin: Water and the Stratum Corneum, by Joachim W. Fluhr, Peter Elsner, Enzo Berardesca, Howard I.

By Joachim W. Fluhr, Peter Elsner, Enzo Berardesca, Howard I. Maibach

Bioengineering of the outside, or extra exactly the biophysical evaluation of epidermis body structure, is relocating quickly from a descriptive method of a deeper figuring out of biophysical and biochemical approaches. This moment variation of the preferred textual content Bioengineering of the surface: Water and Stratum Corneum displays the development within the box, targeting the dramatically enhanced knowing of pores and skin body structure. in particular, it studies the shift in our figuring out of the stratum corneum from an inert surrounding sheet to a biologically lively compartment.

The stratum corneum is the interface among the occasionally harsh atmosphere and the inner turmoil of the human physique. in response to a good number of fresh courses, this e-book explains the mechanisms interested by stratum corneum barrier functionality and hydration. It displays 10 years of development not just of the non-invasive biophysical overview of epidermis body structure parameter, but in addition of the perfection of the on hand units. It brings all study on epidermal water and transepidermal water loss in well-being and disorder updated with the revision of current chapters in addition to further chapters from new members on hydration and itching. This version additionally comprises new directions at the standardization of measurements.

Bioengineering of the outside will increase conversation in the study group and may be precious for scientists within the dermis bioengineering box via offering equipment that provide trustworthy and reproducible ways for product trying out within the pharmaceutical and beauty industries, in addition to for easy study

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Bioengineering of the Skin: Water and the Stratum Corneum, 2nd Edition

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Extra info for Bioengineering of the Skin: Water and the Stratum Corneum, 2nd Edition

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Phase behavior and aggregate structure in mixtures of dioleoylphosphatidylethanolamine and poly(ethylene glycol)-lipids, Biophys. , 80, 313, 2001. 55. L. , Modulation of membrane fusion by asymmetric transbilayer distribution of amino lipids, Biochemistry, 33, 12573, 1994. 56. , Skin barrier formation: the membrane folding model, J. Invest. , 117, 823, 2001. 57. G. , Permeability of dimyristoyl phosphatidyl choline/dipalmitoyl phosphatidylcholine bilayer membranes with coexisting gel and liquid-crystalline phases, Biophys.

117, 830, 2001. 65. , Does the single gel phase exist in stratum corneum? J. Invest. , 118, 897, 2002. 66. Ge, M. et al. Electron spin resonance characterization of liquid ordered phase of detergent-resistant membranes from RBL-2H3 cells, Biophys. , 77, 925, 1999. 67. M. , Epidermal lipid liposomes: a novel non-phospholipid membrane system, Biochem. Soc. , 7, 1129, 1979. 68. W. et al. Preparation of liposomes from stratum corneum lipids, J. Invest. , 87, 582, 1986. 69. , Effect of epidermal acylglucosylceramides and acylceramides on the morphology of liposomes prepared from stratum corneum lipids, Biochim.

17 III. 18 IV. 20 V. 21 VI. 21 VII. 22 VIII. 23 IX. 24 I. INTRODUCTION Keratins are a family of proteins produced by certain epidermal cells in higher vertebrates. Their function is to form an interface between the living medium and the external environment. This function is essential, as it helps to maintain the physical and chemical equilibrium without which life could not exist. As an example, body hair contributes to temperature homeostasis, but it also protects the skin against ultraviolet irradiation.

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